- Arsenal: Arsène Wenger (French/since 1996)
- Aston Villa: Alex McLeish (Scottish/newly appointed this summer)
- Blackburn Rovers: Steve Kean (Scottish/since Dec 2010)
- Bolton Wanderers: Owen Coyle (Scottish/Jan 2010)
- Chelsea: André Villas-Boas (Portuguese/Newly appointed this summer)
- Everton: David Moyes (Scottish/since 2002)
- Fulham: Martin Jol (Dutch/Newly appointed this summer)
- Liverpool: Kenny Dalglish (Scottish/since Jan 2011)
- Manchester City: Roberto Mancini (Italian/since Dec 2009)
- Manchester United: Alex Ferguson (Scottish/since 1986)
- Newcastle United: Alan Pardew (English/since Dec 2010)
- Norwich City: Paul Lambert (Scottish/ Since 2009)
- Queens Park Rangers: Neil Warnock (English/Since Mar 2010)
- Stoke City: Tony Pulis (Welsh/since June 2006)
- Sunderland: Martin O’Neill (Irish/since Dec 2011)
- Swansea City: Brendan Rodgers (Northern Irish/since July 2010)
- Tottenham Hotspur: Harry Redknapp (English/ since Oct 2008)
- West Bromwich Albion: Roy Hodgson (English/since Feb 2011)
- Wigan Athletic: Roberto Martínez (Spanish/since the summer of 2009)
- Wolverhampton Wanderers: Mick McCarthy (English/since July 2006)
Managerial Changes:
| Team | New Manager | Departed Manager | Date of Departure | Date of Appointment | Reason |
| Sunderland | Martin O’Neill | Steve Bruce | 30th Nov 2011 | 3rd Dec 2011 | Sacked |
